Role of CADD in drug discovery

 Different CADD techniques and their applications

 Various strategies to design and develop new drug like molecules.

 Working with molecular modeling softwares to design new drug

molecules

 The in silico virtual screening protocols

Introduction to the course

PHARMACEUTICAL PROCESS CHEMISTRY (MPC 204T)

Scope

Process chemistry is often described as scale up reactions, taking them from small quantities created in the research lab to the larger quantities that are needed for further testing and then to even larger quantities required for commercial production. The goal of a process chemist is to develop synthetic routes that are safe, cost-effective, environmentally friendly, and efficient. The subject is designed to impart knowledge on the development and optimization of a synthetic route/s and the pilot plant procedure for the manufacture of Active Pharmaceutical Ingredients (APIs) and new chemical entities (NCEs) for the drug development phase.

Objectives

At completion of this course it is expected that students will be able to understand

□ The strategies of scale up process ofapis and intermediates

The various unit operations and various reactions in process chemistry