Course Title Hormone Action & Metabolic Disorder (LSC 4008)
1. Characteristics of hormone system, Classification.
2. Molecular basis of hormone action, hormone receptors, cAMP, protein kinase other intracellular messenger like Ca++ and
phosphoinositides.
3. GTP binding proteins, phospholipase, inositol triphosphate and diacyl glycerol.
4. Assay of hormones.
5. Mechanism of action of insulin receptors and tyrosine kinase growth factors.
6. Diabetes regulation of insulin/glucagon and its significance.
7. Hormonal regulation of carbohydrate, fat and protein metabolism.
8. The hypothalamus and pituitary, over and under secretion of pituitary hormones.
9. Hormones and cancer.
10. Thyroid hormone — Mechanisms of action and pathophysiology.
11. Hormones regulating calcium metabolism, calcium as a second messenger, calmodulin.
12 Classification and mechanism of action of catecholamines, neurohormones and substance P. Biomedical importance.
13. Hormones of the gonads, testosterone and estrogens mechanism of action and pathophysiology.
14. Gastrointestinal and neural hormone like secretion like secretion, substance P, neurotensin their mechanism of action.
- Teacher: Sudhir Kumar Awasthi